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the safety and efficacy of tamoxifen in these patients beyond one year of treatment has not been studied.

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in recent years, studies have established that aromatase inhibitors are more effective than tamoxifen in treating breast cancer in women with hormone receptor-positive early breast cancer.

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this is true whether you take medications like tamoxifen, or if your body is going through changes on its own.

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exclusion criteria included premenopausal status; hormone receptor negative primary tumor; metachronous contralateral primary breast cancers diagnosed at different times ; history of other cancer, except nonmelanoma skin cancer or carcinoma in situ of the cervix; and prior tamoxifen.

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study looked at women with dcis and compared those who took tamoxifen for 5 years with others who took a placebo.


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